From Anirva, the maker of Dermal Radiance. This article is general information, not medical advice. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Pomegranate is a red fruit that is rich in plant compounds called polyphenols. It is sold as juice and as an extract in supplements. Here we look at what pomegranate contains and what human trials show for skin. We also cover the amount in Dermal Radiance and safety.
In this article
- Pomegranate is rich in polyphenols. The main ones are punicalagins and ellagic acid. [2]
- Three human trials have tested pomegranate by mouth for skin. They ran for four weeks to three months. [3][4][5]
- In one trial, skin handled more UV light. After 12 weeks of extract or juice, it took more UV light to redden the skin than with placebo. [3]
- In another trial, a wrinkle score went down. It fell by 6.2% after four weeks of extract. [4]
- Dermal Radiance contains 15 mg of pomegranate fruit extract. The amount is listed on the label. [6]
Facts at a Glance
| Fact | Detail |
|---|---|
| Ingredient and form | Pomegranate fruit extract, rich in ellagitannins (mainly punicalagins) and ellagic acid [2] |
| Amount in Dermal Radiance | 15 mg [6] |
| Amounts used in the skin studies | 250 mg to 1,000 mg a day (or 8 oz of juice), for 4 weeks to 3 months [3][4][5] |
| Kinds of evidence | Lab antioxidant studies on punicalagins and ellagic acid; 3 small human trials by mouth, testing extract, juice, or a combination with Polypodium leucotomos [2][3][4][5] |
| Human studies cited here | 3 studies, 18 to 74 people each |
| Regulatory guidance | Juice believed to be safe; extract may also be safe; no established upper limit [1] |
What Is Pomegranate?
Pomegranate is the fruit of a small tree that comes from the Middle East. It is now grown in many places, including the Mediterranean region and the Southwestern United States. [1]
The fruit contains polyphenols called ellagitannins. The main ones are the punicalagins, which account for more than half of its antioxidant activity. It also contains ellagic acid and red pigments called anthocyanins. [2]
How Might Pomegranate Work in Skin?
Antioxidant compounds
Punicalagins and ellagic acid act as antioxidants in lab tests. [2]
Help from gut bacteria
The body does not use ellagitannins as they are. Bacteria in the gut turn them into smaller compounds called urolithins, which the body can absorb. [2]
What Does the Research Show?
The research on pomegranate and skin is still growing. Three human trials by mouth are summarized below.
| Study | Who and How Long | What Was Taken | What It Found |
|---|---|---|---|
| Henning 2019 [3] | 74 women, 12 weeks | 1,000 mg extract, juice or placebo | Skin needed more UV light to redden with extract and with juice |
| Chakkalakal 2022 [4] | 18 adults finished, 4 weeks | 250 mg extract or placebo | Wrinkle score fell by 6.2% with extract and rose by 1% with placebo |
| Emanuele 2017 [5] | 40 adults, 3 months | 480 mg of a pomegranate and Polypodium mix, or Polypodium alone | Hydration and elasticity improved in both groups |
Skin and UV light
In the 2019 trial, women aged 30 to 45 took pomegranate extract, 8 ounces of juice or a placebo every day. After 12 weeks, it took more UV light to cause redness in both pomegranate groups than in the placebo group. [3]
Pomegranate is not a sunscreen. Experts suggest daily sunscreen and shade for sun care.
Wrinkle score
The 2022 trial was randomized, double-blind and placebo-controlled. The extract provided 75 mg of punicalagins a day. [4]
Pomegranate with Polypodium Leucotomos
In the 2017 trial, a skin redness index fell more with the mix than with Polypodium leucotomos alone. [5] Dermal Radiance contains both of these ingredients. [6]
How Much Pomegranate Is in Dermal Radiance?
| Source | Pomegranate Extract a Day | Notes |
|---|---|---|
| Dermal Radiance (2 capsules) | 15 mg | Fruit extract, from the label [6] |
| Chakkalakal 2022 | 250 mg | [4] |
| Henning 2019 | 1,000 mg | Or 8 ounces of juice [3] |
Dermal Radiance provides 15 mg of pomegranate fruit extract. This is well below the 250 mg and 1,000 mg used in the trials.
What the Research Does Not Show Yet
- The trials were small, with 18 to 74 people. In the 2022 trial, 28 people started and 18 finished. [4]
- In the 2019 trial, the women knew which product they were taking. [3]
- The 2017 trial had no placebo group, and its abstract does not give the amount of pomegranate in the mix. [5]
- We found no study of pomegranate with the other Dermal Radiance ingredients.
Safety and Interactions
The National Institutes of Health says pomegranate juice is believed to be safe, and that the extract may also be safe. Pomegranate does not usually cause side effects. Some people have digestive symptoms, and allergic reactions have been reported. [1]
Pomegranate juice may raise the risk of bleeding in people who take the blood thinner warfarin. A muscle problem has also been reported with statins. [2] If you take either of these medicines, talk to your doctor before you take pomegranate.
Pomegranate is a common food, and its extract has been tested in people for up to three months. [3][5] A few points can help you use it well:
Pomegranate Is One Part of Dermal Radiance
Dermal Radiance is a daily two-capsule supplement with 20 vitamins, minerals and plant extracts. They were chosen to support healthy collagen, skin firmness and elasticity, and radiance. Pomegranate fruit extract is one of them.
Dermal Radiance has not been clinically tested as a finished product. For this reason, we cannot say how its ingredients work together.
If you take Dermal Radiance, you are not relying on pomegranate alone. It is one of 20 ingredients in each serving. Every ingredient and amount is listed on the label. [6]
About Dermal Radiance
A daily two-capsule formula with 20 vitamins, minerals and plant extracts, including 15 mg of pomegranate fruit extract, per serving. Dermal Radiance hasn't been clinically tested as a finished formula. The label lists every ingredient and its amount.
See the Dermal Radiance product page →If You Are Deciding
Pomegranate is a polyphenol-rich fruit with three small human skin trials behind it. [3][4][5] If you would like to try Dermal Radiance, the directions are two capsules a day with a meal. [6]
The Short Version
Pomegranate is a fruit rich in polyphenols such as punicalagins and ellagic acid. Three small human trials have tested it by mouth for skin, over four weeks to three months. Dermal Radiance provides 15 mg of pomegranate fruit extract.
Frequently Asked Questions
References
- National Center for Complementary and Integrative Health, National Institutes of Health. Pomegranate. Last updated April 2025.
- Memorial Sloan Kettering Cancer Center. About Herbs: Pomegranate. Last updated November 11, 2022.
- Henning SM, Yang J, Lee RP, Huang J, Hsu M, Thames G, Gilbuena I, Long J, Xu Y, Park EH, Tseng CH, Kim J, Heber D, Li Z. Pomegranate juice and extract consumption increases the resistance to UVB-induced erythema and changes the skin microbiome in healthy women: a randomized controlled trial. Sci Rep. 2019;9(1):14528. doi:10.1038/s41598-019-50926-2. PMID: 31601842.
- Chakkalakal M, Nadora D, Gahoonia N, Dumont A, Burney W, Pan A, Chambers CJ, Sivamani RK. Prospective randomized double-blind placebo-controlled study of oral pomegranate extract on skin wrinkles, biophysical features, and the gut-skin axis. J Clin Med. 2022;11(22):6724. doi:10.3390/jcm11226724.
- Emanuele E, Bertona M, Biagi M. Comparative effects of a fixed Polypodium leucotomos/Pomegranate combination versus Polypodium leucotomos alone on skin biophysical parameters. Neuro Endocrinol Lett. 2017;38(1):38-42. PMID: 28456146.
- Anirva. Dermal Radiance Supplement Facts label and product page.
