From Anirva, the maker of Dermal Radiance. This article is general information, not medical advice. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Vitamin B12 is a B vitamin. The body needs it to make DNA and healthy red blood cells. Here we look at what vitamin B12 does and how that relates to skin. We also cover the amount in Dermal Radiance, food sources and safety.
In this article
- Vitamin B12 is needed to make DNA. The body also needs it for healthy red blood cells and for the nervous system. [1]
- Regulators accept its role in cell division. In Europe, labels may say that vitamin B12 has a role in the process of cell division. [3]
- Low vitamin B12 shows up in the skin. The signs include pale skin, and changes in skin color, hair and nails. [1][5]
- Dermal Radiance uses methylcobalamin. This is one of the two forms of vitamin B12 that are active in the body. [1][4]
- Dermal Radiance contains 100 mcg of vitamin B12. That is 4,167% of the Daily Value. [4]
Facts at a Glance
| Fact | Detail |
|---|---|
| Ingredient and form | Vitamin B12, as methylcobalamin — a water-soluble vitamin containing cobalt [1] |
| Amount in Dermal Radiance | 100 mcg — 4,167% of the Daily Value [4] |
| Amounts used in the research | No skin-specific trial amount found; absorption studies suggest the body takes in about half of a 1 mcg dose and about 2% of a 500 mcg dose [1] |
| Kinds of evidence | Deficiency-sign observations and a recognized role in DNA synthesis and cell division — no human skin trial of a vitamin B12 supplement found [1][5] |
| Human studies cited here | 0 — this article summarizes established nutrition science and a dermatology review, not a skin-outcome trial |
| Regulatory guidance | No upper limit set; EU permits a claim on the role of vitamin B12 in cell division [1][3] |
What Is Vitamin B12?
Vitamin B12 is a water-soluble vitamin. It contains the mineral cobalt, so its forms are called cobalamins. Two forms are active in the body, and methylcobalamin is one of them. [1]
Adults need 2.4 mcg a day. In the United States, the average intake from food and drinks is 5.84 mcg for men and 3.69 mcg for women. [1]
How Might Vitamin B12 Work in Skin?
New cells need DNA
The body makes new cells when cells divide, and each new cell needs its own copy of DNA. Vitamin B12 is needed to make DNA. [1] In Europe, labels may say that vitamin B12 has a role in the process of cell division. [3]
What deficiency tells us
Low vitamin B12 can show in the skin. The signs include pale skin and a sore tongue. [1] A dermatology review also lists changes in skin color, most commonly, and changes in hair and nails. [5]
What Does the Research Show?
The research on vitamin B12 supplements and skin is still growing. The points below are the ones that trusted sources agree on.
| Source | What It Says |
|---|---|
| National Institutes of Health [1] | Vitamin B12 is needed to make DNA and healthy red blood cells. Pale skin is one sign of a lack of it |
| European regulators [3] | Vitamin B12 has a role in the process of cell division |
| Dermatology review, 2015 [5] | A lack of vitamin B12 can lead to changes in skin color, hair and nails |
How Much Vitamin B12 Is in Dermal Radiance?
| Source | Vitamin B12 a Day | Notes |
|---|---|---|
| Dermal Radiance (2 capsules) | 100 mcg | 4,167% of the Daily Value, from the label, as methylcobalamin [4] |
| Adult daily need | 2.4 mcg | [1] |
| Average intake from food, US | 5.84 mcg (men), 3.69 mcg (women) | [1] |
| A typical multivitamin | 5 to 25 mcg | [1] |
Dermal Radiance provides 100 mcg of vitamin B12 as methylcobalamin. The body absorbs a smaller share of vitamin B12 as the dose goes up — it takes in about half of a 1 mcg dose, and about 2% of a 500 mcg dose. [1]
Food Sources of Vitamin B12
Vitamin B12 is found in animal foods and in fortified foods. Plant foods do not naturally contain it: [1]
- Beef liver, 3 ounces: 70.7 mcg
- Salmon, 3 ounces: 2.6 mcg
- Beef, 3 ounces: 2.4 mcg
What the Research Does Not Show Yet
- We found no human trial of vitamin B12 by mouth that measured skin in healthy adults.
- Most people in the United States get enough vitamin B12 from food. [1]
- We found no study of vitamin B12 combined with the other Dermal Radiance ingredients.
Safety and Interactions
Vitamin B12 has a good safety record. No upper limit has been set, because it has a low potential for harm. The body does not store excess amounts. [1][2]
Some medicines can lower the amount of vitamin B12 that the body absorbs. These include metformin and medicines that reduce stomach acid. [1]
A dermatology review reports that vitamin B12 given as a medical treatment has been linked with acne and rosacea in some people. [5]
Most people already get vitamin B12 from fish, meat, eggs and dairy foods. [1] A few points can help you use it well:
Vitamin B12 Is One Part of Dermal Radiance
Dermal Radiance is a daily two-capsule supplement with 20 vitamins, minerals and plant extracts. They were chosen to support healthy collagen, skin firmness and elasticity, and radiance. Vitamin B12 is one of them.
Dermal Radiance has not been clinically tested as a finished product. For this reason, we cannot say how its ingredients work together.
If you take Dermal Radiance, you are not relying on vitamin B12 alone. It is one of 20 ingredients in each serving. Every ingredient and amount is listed on the label. [4]
About Dermal Radiance
A daily two-capsule formula with 20 vitamins, minerals and plant extracts, including 100 mcg of vitamin B12 (as methylcobalamin) per serving. Dermal Radiance hasn't been clinically tested as a finished formula. The label lists every ingredient and its amount.
See the Dermal Radiance product page →If You Are Deciding
Vitamin B12 is a basic nutrient for making DNA and healthy red blood cells. [1] Regulators in Europe accept its role in cell division. [3] If you would like to try Dermal Radiance, the directions are two capsules a day with a meal. [4]
The Short Version
Vitamin B12 is a B vitamin that the body needs to make DNA and healthy red blood cells. In Europe, labels may say that it has a role in the process of cell division. Dermal Radiance provides 100 mcg of vitamin B12 as methylcobalamin.
Frequently Asked Questions
References
- National Institutes of Health, Office of Dietary Supplements. Vitamin B12: Fact Sheet for Health Professionals. Updated July 2, 2025.
- Linus Pauling Institute, Oregon State University. Micronutrient Information Center: Vitamin B12. Updated October 2023.
- European Commission. Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods.
- Anirva. Dermal Radiance Supplement Facts label and product page.
- Brescoll J, Daveluy SD. A review of vitamin B12 in dermatology. Am J Clin Dermatol. 2015;16(1):27-33. doi:10.1007/s40257-014-0107-3. PMID: 25559140.
