Biotin for Skin, Hair and Nails: What the Research Shows

Biotin is a B vitamin that skin, hair and nails all need. Here is what the research shows, and how much is in Dermal Radiance.

Skincare Ingredients 10 min read October 06, 2026
Biotin for Skin, Hair and Nails: What the Research Shows

From Anirva, the maker of Dermal Radiance. This article is general information, not medical advice. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Biotin may be the most familiar name in the "skin, hair and nails" aisle. If you have looked at supplements for any of the three, you have almost certainly seen it on a label. Biotin is a B vitamin that the body needs every day. Here we look at what biotin does and what the research shows for skin, hair and nails, how much is in Dermal Radiance, food sources and safety.

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Key takeaways
  • Biotin is a B vitamin, also called vitamin B7. It helps five enzymes that process fats, sugars and amino acids [1].
  • Regulators accept the link with normal skin and hair. In Europe, labels may say that biotin contributes to the maintenance of normal skin and normal hair [2][3].
  • Low biotin shows up in skin, hair and nails. The known signs are a scaly rash, thinning hair and brittle nails [1].
  • In small studies, biotin supported nails. People with thin, brittle nails had thicker or firmer nails after several months of biotin [1].
  • Dermal Radiance contains 300 mcg of biotin. That is 1,000% of the Daily Value [5].

What is biotin?

Biotin is a water-soluble B vitamin, also called vitamin B7, that is found in many foods and sold as a supplement [1].

The body uses biotin as a helper for five enzymes called carboxylases, which carry out key steps in how the body handles fats, sugars and amino acids. Biotin also plays a part in gene regulation and cell signaling [1].

Adults need about 30 mcg of biotin a day. This figure is called an Adequate Intake, because there is not enough data to set a more exact requirement [1].

How might biotin work in skin?

Making fats

The outer layer of skin relies on fats to hold in moisture. Biotin-dependent enzymes carry out key steps in the way the body makes and uses fatty acids [1].

What deficiency tells us

When the body runs very low on biotin, skin, hair and nails are among the places it shows. The signs include a scaly, red rash, thinning hair and brittle nails, which tells us that these tissues need biotin to stay normal [1].

What does the research show?

The research on biotin supplements is still growing. The clearest findings are about nails, and about people whose biotin was low.

Regulators accept the link with normal skin and hair

In 2010, the European Food Safety Authority reviewed health claims for biotin. These included claims about normal skin, hair and nails [2]. European law now allows labels to say that biotin contributes to the maintenance of normal skin and of normal hair [3].

Three small studies on nails

The National Institutes of Health describes three small studies in people with thin or brittle nails. All three used 2.5 mg of biotin a day [1].

  • In the largest, 45 people took biotin for about 5.5 months. Nails became firmer and harder in 41 of them (91%).
  • In another, 35 people took biotin for 6 to 15 months, and 22 of them (63%) improved.
  • In a study of women with brittle nails, nail thickness rose by 25% in the 8 women who were measured before and after.
A 2017 review of hair and nail reports

In 2017, researchers reviewed the published reports of biotin used for hair and nail changes. They found 18 cases, and every person improved after taking biotin. Each one had an underlying cause for the hair or nail changes [4].

Study summary
Study People Amount a day Length Main result
Nail study 1 [1] 45 people with thin, brittle nails 2.5 mg About 5.5 months Firmer, harder nails in 41 people (91%)
Nail study 2 [1] 35 people with brittle nails 2.5 mg 6–15 months Improvement in 22 people (63%)
Nail study 3 [1] 22 women with brittle nails 2.5 mg 6–15 months Nail thickness up 25% in 8 women measured
Patel et al., 2017 [4] 18 published cases Varied Varied All improved; each had an underlying cause

How much biotin is in Dermal Radiance compared with the studies?

Source Biotin a day Notes
Dermal Radiance (2 capsules) 300 mcg 1,000% of the Daily Value, from the label [5]
Adult daily need (Adequate Intake) 30 mcg [1]
Typical intake from food 35–70 mcg Western diets [1]
Nail studies 2,500 mcg (2.5 mg) Taken for 5 to 15 months [1]

Dermal Radiance provides 300 mcg of biotin. This is ten times the daily need, and it is lower than the 2.5 mg used in the nail studies. Those studies tested biotin by itself, so their results do not describe Dermal Radiance as a whole.

Food sources of biotin

Biotin is found in many foods. Some examples [1]:

  • Beef liver, 3 ounces cooked: 30.8 mcg
  • One whole egg, cooked: 10 mcg
  • Canned pink salmon, 3 ounces: 5 mcg
  • Pork chop, 3 ounces cooked: 3.8 mcg
  • Sunflower seeds, a quarter cup: 2.6 mcg
  • Sweet potato, half a cup cooked: 2.4 mcg

Raw egg white contains a protein called avidin, which binds biotin and blocks its absorption. Cooking changes avidin, so cooked eggs do not have this effect [1].

What the research does not show yet

  • The nail studies were small, and the people in them had thin or brittle nails to begin with [1].
  • For hair and skin, the published evidence is mostly individual case reports [1][4].
  • Biotin deficiency is rare, so we know less about extra biotin in people who already get enough [1].
  • We found no study of biotin combined with the other Dermal Radiance ingredients.

Safety and interactions

Biotin has a good safety record. No upper limit has been set, because there is no evidence that biotin is toxic at high intakes. Studies found no unwanted effects at 10 to 50 mg a day [1].

There is one point to know about blood tests. High intakes of biotin can affect some lab tests, including thyroid tests and a heart test called troponin, and give a false result. This has been reported at 10 mg a day or more [1]. Dermal Radiance has 0.3 mg, which is far below that amount. The FDA advises doctors to ask patients about supplements that contain biotin, so it helps to mention yours before a blood test [1].

Some seizure medicines, taken for a year or more, are linked with lower biotin levels [1].

Good to know Biotin is well tolerated, and no upper limit has been set for it [1]. A few points can help you use it well:
  • Nails and hair grow slowly. The nail studies ran for 5 to 15 months [1].
  • Many hair, skin and nail products contain biotin, so check the labels of the other supplements you take.
  • Before a blood test, tell your doctor or pharmacist that you take a supplement with biotin.

Biotin is one part of Dermal Radiance

Dermal Radiance is a daily two-capsule supplement with 20 vitamins, minerals and plant extracts. They were chosen to support healthy collagen, skin firmness and elasticity, and radiance. Biotin is one of them.

Dermal Radiance has not been clinically tested as a finished product. For this reason, we cannot say how its ingredients work together. The studies in this article tested biotin by itself.

If you take Dermal Radiance, you are not relying on biotin alone. It is one of 20 ingredients in each serving. Every ingredient and amount is listed on the label [5].

Anirva · Dermal Radiance
A daily skin supplement with 20 ingredients

Biotin is one of 20 vitamins, minerals and plant extracts in Dermal Radiance, each listed with its amount on the label. Two capsules a day with a meal.

See the full ingredient list

If you are deciding

Biotin is a sensible part of a skin, hair and nail formula, because all three need it to stay normal [1][3]. Most people get the basic amount from food, and a supplement adds to that. If you would like to try Dermal Radiance, the directions are two capsules a day with a meal [5].

The short version

Biotin is a B vitamin that helps the body process fats, sugars and amino acids. Skin, hair and nails all show it when biotin runs low, and in small studies biotin supported thicker, firmer nails. Dermal Radiance provides 300 mcg, which is ten times the daily need.

Frequently asked questions

Does biotin help skin?

The body needs biotin to process fats, and skin relies on fats to hold in moisture [1]. In Europe, labels may say biotin contributes to the maintenance of normal skin [3].

Does biotin help hair and nails?

In three small studies, people with thin or brittle nails had firmer or thicker nails after taking 2.5 mg of biotin a day for several months [1]. In 18 published reports on hair and nails, each person improved after taking biotin [4].

How much biotin do adults need?

About 30 mcg a day. Typical Western diets provide 35 to 70 mcg [1].

How much biotin is in Dermal Radiance?

Each serving has 300 mcg, which is 1,000% of the Daily Value [5].

Is it safe to take biotin every day?

Biotin has a good safety record, and no upper limit has been set. Studies found no unwanted effects at 10 to 50 mg a day [1].

Can biotin affect blood tests?

High intakes, such as 10 mg a day, can affect some lab tests [1]. Tell your doctor about any supplement with biotin before a blood test.

What foods are high in biotin?

Beef liver, eggs, salmon, pork, sunflower seeds and sweet potatoes are good sources. One cooked egg has about 10 mcg [1].

Do raw eggs block biotin?

Raw egg white contains avidin, which binds biotin and blocks its absorption. Cooked eggs do not have this effect [1].

  1. National Institutes of Health, Office of Dietary Supplements. Biotin: Fact Sheet for Health Professionals. Updated January 10, 2022. https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/ (accessed October 3, 2026).
  2. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to biotin and maintenance of normal skin and mucous membranes, maintenance of normal hair, maintenance of normal nails and other functions. EFSA Journal. 2010;8(10):1728. doi:10.2903/j.efsa.2010.1728.
  3. European Commission. Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods. https://eur-lex.europa.eu/eli/reg/2012/432 (accessed October 3, 2026).
  4. Patel DP, Swink SM, Castelo-Soccio L. A review of the use of biotin for hair loss. Skin Appendage Disord. 2017;3(3):166-169. doi:10.1159/000462981. PMID: 28879195.
  5. Anirva. Dermal Radiance Supplement Facts label and product page. https://anirva.com/pages/anti-aging-skin-supplement-dermal-radiance (accessed October 3, 2026).
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