From Anirva, the maker of Dermal Radiance. This article is general information, not medical advice. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Skin renews itself all the time. Old cells are shed and new ones take their place, and that work needs a steady supply of nutrients. Many people who care about their skin ask whether zinc is one of the nutrients that matter. Zinc is a mineral the body needs every day. Here we look at what zinc does in skin and what the research shows, zinc picolinate, how much is in Dermal Radiance, and safety.
In this article
- Zinc is an essential mineral, and skin holds a good share of it. About 5% of the body's zinc is in the skin. [1][2]
- Regulators accept the link with normal skin. In Europe, labels may say that zinc contributes to the maintenance of normal skin. [3][4]
- Low zinc shows up in skin. Slow wound healing, hair loss and skin changes are known signs of zinc deficiency. [1][2]
- Zinc picolinate was absorbed well in a human study. In 15 adults, it raised zinc levels in hair, urine and red blood cells over four weeks. [5]
- Dermal Radiance contains 30 mg of zinc. That is 273% of the Daily Value, as zinc picolinate. [7]
Facts at a Glance
| Fact | Detail |
|---|---|
| Ingredient and form | Zinc, as zinc picolinate [7] |
| Amount in Dermal Radiance | 30 mg — 273% of the Daily Value [7] |
| Amounts used in the absorption study | 50 mg a day, for 4 weeks per form tested [5] |
| Kinds of evidence | Government fact sheet; a 2018 review of lab/animal/human findings; an EFSA regulator review; a 1987 absorption study; a 2024 industry-funded review [1][2][3][5][6] |
| Human studies cited here | 1 absorption study of 15 adults; broader deficiency/intake data from government and review sources |
| Regulatory guidance | Adult upper limit: 40 mg/day (food + supplements); EU permits a normal-skin maintenance claim [1][4] |
What Is Zinc?
Zinc is an essential mineral. The body cannot make it, so it must come from food or supplements, and hundreds of enzymes need zinc to do their work. [1]
Zinc plays a part in making proteins and DNA, in cell division, in immune function and in wound healing. [1] Adults need 8 mg a day (women) or 11 mg a day (men). [1]
Skin is the third most zinc-rich tissue in the body. The outer layer of skin holds more zinc than the deeper layer. [2]
How Might Zinc Work in Skin?
Cell renewal
Skin cells divide often, and cell division needs zinc. [1] In lab studies, zinc at suitable levels helped skin surface cells survive and multiply. [2]
Collagen and the deeper skin layer (animal studies)
Cells move zinc in and out through proteins called zinc transporters. In animal studies, one of these transporters was needed for the deeper skin layer to form well and for collagen to be laid down. [2] This is a possible pathway for supporting collagen, and it has not yet been shown in people.
Wound healing
Zinc is involved in wound healing. [1] Several zinc-dependent enzymes take part in rebuilding skin after an injury. [2]
What Does the Research Show?
The research on zinc supplements and healthy skin is still growing. Most of what we know comes from the study of zinc needs and zinc deficiency, not from skin trials.
Regulators accept the link with normal skin
In 2010, the European Food Safety Authority reviewed health claims for zinc. These included claims about normal skin, hair and nails, and about protein synthesis and cell division. [3] European law now allows labels to say that zinc contributes to the maintenance of normal skin. [4]
This wording is about meeting the body's need for zinc, and it does not say that extra zinc improves skin in people who already get enough.
What happens when zinc is low
Zinc deficiency affects skin in clear ways. It can slow wound healing and cause hair loss. [1][2] Severe deficiency causes a typical rash around the mouth and on the hands and feet. [2]
Who may run low
About 15% of American adults take in less zinc than the estimated need. [1] Groups more likely to run low include: [1]
- Vegetarians and vegans
- People with digestive disorders, or who have had weight-loss surgery
- Women who are pregnant or breastfeeding
- People with alcohol use disorder
| Source | Type | What It Shows |
|---|---|---|
| NIH Office of Dietary Supplements [1] | Government fact sheet | Zinc is needed for cell division, protein synthesis and wound healing; deficiency slows healing |
| Ogawa et al., 2018 [2] | Review of lab, animal and human findings | Skin holds about 5% of body zinc; zinc supports skin cells and collagen in lab and animal studies |
| EFSA, 2010 [3] | Regulator review | Reviewed zinc claims for normal skin, hair and nails |
| Barrie et al., 1987 [5] | Absorption study, 15 adults | Zinc picolinate raised zinc levels in hair, urine and red blood cells |
Zinc Picolinate and Other Forms
Dermal Radiance uses zinc picolinate. [7] Supplements also come as zinc gluconate, citrate, sulfate, acetate, oxide and glycinate. [1][6]
In 1987, a double-blind study gave 15 healthy adults 50 mg of zinc a day in three forms, and a placebo, for four weeks each. Zinc picolinate raised zinc levels in hair, urine and red blood cells. Zinc citrate and zinc gluconate showed no significant change, and neither did the placebo. Zinc in blood serum did not change significantly with any form. The authors concluded that picolinic acid can improve zinc absorption. [5]
Other studies give a mixed picture. In a single-dose study of 12 women, zinc glycinate was absorbed most, and zinc picolinate ranked third of four forms. A 2024 review concluded that the evidence on zinc forms is limited and comes from small studies. A supplement company funded that review. [6]
The National Institutes of Health reports that the body absorbs about 61% of zinc from zinc citrate or gluconate, and about 50% from zinc oxide. [1]
How Much Zinc Is in Dermal Radiance Compared With Daily Needs?
| Source | Zinc a Day | Notes |
|---|---|---|
| Dermal Radiance (2 capsules) | 30 mg | 273% of the Daily Value, as zinc picolinate [7] |
| Adult daily need (RDA) | 8 mg (women), 11 mg (men) | [1] |
| Average intake from food, US adults | 9.2 mg (women), 13 mg (men) | [1] |
| Absorption study | 50 mg | Four weeks for each form [5] |
| Adult upper limit | 40 mg | From food and supplements together [1] |
Dermal Radiance provides 30 mg, which is well above the daily need and below the 40 mg upper limit. The upper limit counts zinc from food as well as supplements. [1]
An average diet adds about 9 to 13 mg of zinc a day. [1] If you also take another supplement with zinc, it helps to add up your total.
Food Sources of Zinc
Meat, shellfish and seeds are good sources. Some examples: [1]
- Oysters, 3 ounces: 28 to 32 mg
- Beef sirloin, 3 ounces: 3.8 mg
- Blue crab, 3 ounces: 3.2 mg
- Pumpkin seeds, 1 ounce: 2.2 mg
- Pork chop, 3 ounces: 1.9 mg
Whole grains, beans and some other plant foods contain compounds called phytates. Phytates bind zinc in the gut, so the body absorbs less zinc from these foods. [1]
What the Research Does Not Show Yet
- We found no placebo-controlled trial of zinc by itself that measured skin firmness, elasticity or lines in healthy adults.
- The collagen findings come from animal and lab studies. [2]
- The evidence on which zinc form is absorbed most is limited and mixed. [6]
- We found no study of zinc combined with the other Dermal Radiance ingredients.
Safety and Interactions
The adult upper limit for zinc is 40 mg a day from food and supplements. It was set because higher intakes can lower copper levels in the body. [1]
Taking 50 mg or more for weeks can reduce copper absorption, reduce immune function and lower HDL cholesterol. High zinc intakes can cause nausea, stomach upset, headache and loss of appetite. [1] Dermal Radiance does not contain copper. [7]
Zinc can interact with some medicines: [1]
- Quinolone and tetracycline antibiotics. The advice is to take the antibiotic at least 2 hours before, or 4 to 6 hours after, a zinc supplement.
- Penicillamine. The advice is to take it and zinc at least 1 hour apart.
- Thiazide diuretics. These raise the amount of zinc lost in urine.
Iron supplements with 25 mg of iron or more can reduce zinc absorption when taken at the same time. [1]
Zinc is a familiar nutrient, and most people take it without problems at usual amounts. A few points can help you use it well:
- Add up the zinc from all your supplements, such as a multivitamin, and keep the total at or below 40 mg a day. [1]
- Take Dermal Radiance with a meal, as the directions say. [7]
- If you take antibiotics, a diuretic or other prescription medicines, ask your doctor or pharmacist about timing before you start.
Zinc Is One Part of Dermal Radiance
Dermal Radiance is a daily two-capsule supplement with 20 vitamins, minerals and plant extracts. They were chosen to support healthy collagen, skin firmness and elasticity, and radiance. Zinc is one of them.
Dermal Radiance has not been clinically tested as a finished product. For this reason, we cannot say how its ingredients work together. The research in this article is about zinc by itself.
If you take Dermal Radiance, you are not relying on zinc alone. It is one of 20 ingredients in each serving. Every ingredient and amount is listed on the label. [7]
About Dermal Radiance
A daily two-capsule formula with 20 vitamins, minerals and plant extracts, including 30 mg of zinc, as zinc picolinate, per serving. Dermal Radiance hasn't been clinically tested as a finished formula. The label lists every ingredient and its amount.
See the Dermal Radiance product page →
About Dermal Radiance
A daily two-capsule formula with 20 vitamins, minerals and plant extracts, including 30 mg of zinc, as zinc picolinate, per serving. Dermal Radiance hasn't been clinically tested as a finished formula. The label lists every ingredient and its amount.
See the Dermal Radiance product page →The Short Version
Zinc is an essential mineral, and skin holds about 5% of the body's supply. The body needs it for cell renewal and wound healing, and low zinc shows up in skin. In a human study, zinc picolinate raised zinc levels in the body. Dermal Radiance provides 30 mg of zinc as zinc picolinate.
Frequently Asked Questions
References
- National Institutes of Health, Office of Dietary Supplements. Zinc: Fact Sheet for Health Professionals. Updated January 6, 2026.
- Ogawa Y, Kinoshita M, Shimada S, Kawamura T. Zinc and skin disorders. Nutrients. 2018;10(2):199. doi:10.3390/nu10020199. PMID: 29439479.
- EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to zinc and maintenance of normal skin, DNA synthesis and cell division, contribution to normal protein synthesis, maintenance of normal hair, maintenance of normal nails and other functions. EFSA Journal. 2010;8(10):1819. doi:10.2903/j.efsa.2010.1819.
- European Commission. Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods.
- Barrie SA, Wright JV, Pizzorno JE, Kutter E, Barron PC. Comparative absorption of zinc picolinate, zinc citrate and zinc gluconate in humans. Agents Actions. 1987;21(1-2):223-228. doi:10.1007/BF01974946. PMID: 3630857.
- Devarshi PP, Mao Q, Grant RW, Mitmesser SH. Comparative absorption and bioavailability of various chemical forms of zinc in humans: a narrative review. Nutrients. 2024;16(24):4269. doi:10.3390/nu16244269. PMID: 39770891.
- Anirva. Dermal Radiance Supplement Facts label and product page.
